ethyl mercaptan sodium salt in N,N-dimethyl-formamide T=140°C; 10 h;

ethyl mercaptan sodium salt in N,N-dimethyl-formamide T=140°C; 10 h;

sodium methylate in methanol T=20°C; Deacetylation; 2 h;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11342940', constants.ctx, '0')">sodium hydroxide</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3739113', constants.ctx, '0')">phenylmethyltriethylammonium bromide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1731042', constants.ctx, '0')">chloroform</a> <br />T=60&deg;C;&nbsp;5&nbsp;h;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1.1: 85 percent / toluene<br />2.1: butyllithium / hexane; tetrahydrofuran / 15 - 20 &deg;C<br />2.2: 78 percent / hexane; tetrahydrofuran / 1 h / 20 &deg;C<br />3.1: 68.3 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.25 h / 20 &deg;C<br />4.1: 32 percent / benzyltriethylammonium bromide; NaOH / CHCl₃; H₂O / 10 h / 60 &deg;C<br /> <br /> &nbsp;