2'-甲基-4'-(2-氧代-1-吡咯烷基)-4-联苯基羧酸合成路线 （共 3 条）
反应条件
palladium on activated charcoal; sodium carbonate in methanol; water T=77.8°C; Suzuki Coupling; 5 h; Inert atmosphereLarge scale; Reagent/catalyst;
参考文献
Ennis, David S.; McManus, Julie; Wood-Kaczmar, Wladyslaw; Richardson, John; Smith, Gillian E.; Carstairs, Alexis
Organic Process Research and Development, 1999 , vol. 3, # 4 p. 248 - 252
反应条件
1: hydrogenchloride / water / 4 h / |Heating 2: sodium carbonate; palladium on activated charcoal / methanol; water / 5 h / 77.8 °C / |Inert atmosphere; |Large scale View Scheme
参考文献
Ennis, David S.; McManus, Julie; Wood-Kaczmar, Wladyslaw; Richardson, John; Smith, Gillian E.; Carstairs, Alexis
Organic Process Research and Development, 1999 , vol. 3, # 4 p. 248 - 252
反应条件
1: tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl; caesium carbonate / toluene / 20 h / 110 °C / |Inert atmosphere 2: sodium carbonate; palladium on activated charcoal / methanol; water / 5 h / 77.8 °C / |Inert atmosphere; |Large scale View Scheme
参考文献
Ennis, David S.; McManus, Julie; Wood-Kaczmar, Wladyslaw; Richardson, John; Smith, Gillian E.; Carstairs, Alexis
Organic Process Research and Development, 1999 , vol. 3, # 4 p. 248 - 252
