2-(2-氯乙酰氨基)-4-噻唑乙酸乙酯合成路线 （共 7 条）
反应条件
pyridine in benzene T=20°C; Acylation; 1 h;
参考文献
Altintas, Handan; Ates, Oeznur; Kocabalkanli, Ayse; Birteksoez, Seher; Oetuek, Guelten
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 3 p. 585 - 590
反应条件
1: acetic acid; hydrogen bromide / 100 °C 2: ethanol / 1 h / 20 °C 3: potassium carbonate / dichloromethane / 18 h / 20 °C / |Cooling with ice View Scheme
参考文献
ChemMedChem, , vol. 8, # 12 p. 1923 - 1929
反应条件
1: ethanol / 1 h / 20 °C 2: potassium carbonate / dichloromethane / 18 h / 20 °C / |Cooling with ice View Scheme
参考文献
ChemMedChem, , vol. 8, # 12 p. 1923 - 1929
反应条件
1: bromine / water / 0.5 h / 0 °C 2: acetic acid; hydrogen bromide / 100 °C 3: ethanol / 1 h / 20 °C 4: potassium carbonate / dichloromethane / 18 h / 20 °C / |Cooling with ice View Scheme
参考文献
ChemMedChem, , vol. 8, # 12 p. 1923 - 1929
参考文献
Bioorganic and Medicinal Chemistry, , vol. 11, # 13 p. 2983 - 2989
反应条件
potassium fluoride; 1,3-di-tert-butyl-1,1,3,3-tetramethyldisilatellurane in acetonitrile 48 h; Ambient temperature;
参考文献
Schultz, Erwin K. V.; Harpp, David N.
Synthesis, 1998 , # 8 p. 1137 - 1140
反应条件
sodium hydroxide in ethanol
3 h;
参考文献
Perrone; Alpegiani; Giudici; et al.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 4 p. 1097 - 1111
