1-(甲氧基羰基)哌啶-4-羧酸合成路线 （共 4 条）
反应条件
sodium hydrogencarbonate in tetrahydrofuran
参考文献
Boto, Alicia; Hernandez, Rosendo; De Leon, Yolanda; Murguia, Jose R.; Rodriguez-Afonso, Abigail
European Journal of Organic Chemistry, 2005 , # 4 p. 673 - 682
反应条件
thionyl chloride in N,N-dimethyl-formamide T=85°C; 0.333333 h;
参考文献
Frolund, Bente; Jorgensen, Anne T.; Tagmose, Lena; Stensbol, Tine B.; Vestergaard, Henrik T.; Engblom, Christine; Kristiansen, Uffe; Sanchez, Connie; Krogsgaard-Larsen, Povl; Liljefors, Tommy
Journal of Medicinal Chemistry, 2002 , vol. 45, # 12 p. 2454 - 2468
反应条件
1.1: 79 percent / NaI; K2CO3 / acetonitrile / 0 - 20 °C
2.1: LDA / tetrahydrofuran / -78 °C
2.2: 94 percent / tetrahydrofuran / -78 - 20 °C
3.1: 99 percent / H2 / 20 percent Pd(OH)2/C / ethyl acetate / 20 °C
View Scheme
参考文献
Boto, Alicia; Hernandez, Rosendo; De Leon, Yolanda; Murguia, Jose R.; Rodriguez-Afonso, Abigail
European Journal of Organic Chemistry, 2005 , # 4 p. 673 - 682
反应条件
[bis(acetoxy)iodo]benzene; iodine in tetrachloromethane
T=80°C; 5 h; Irradiation;
参考文献
Boto, Alicia; Hernandez, Rosendo; De Leon, Yolanda; Murguia, Jose R.; Rodriguez-Afonso, Abigail
Tetrahedron Letters, 2004 , vol. 45, # 37 p. 6841 - 6845
