2-羟基-3-甲基-6-硝基喹噁啉合成路线 （共 6 条）
反应条件
sulfuric acid; water T=20 - 70°C; Condensation; 1 h;
参考文献
Horner et al.
Justus Liebigs Annalen der Chemie, 1953 , vol. 579, p. 212,220
参考文献
Horner et al.
Justus Liebigs Annalen der Chemie, 1953 , vol. 579, p. 212,220
反应条件
1: POCl3 2: 60 percent / 70percent hydrazine hydrate / ethanol / 3 h / Heating View Scheme
参考文献
Nasielski, J.; Nasielski-Hinkens, R.; Heilporn, S.; Rypens, C.; Declercq, J. P.
Bulletin des Societes Chimiques Belges, 1988 , vol. 97, # 11-12 p. 983 - 992
反应条件
1: POCl3 2: 60 percent / 70percent hydrazine hydrate / ethanol / 3 h / Heating 3: NaNO2 / acetic acid; H2O / 0 deg C, 30 min; room temp., 1 h 4: CrO3 View Scheme
参考文献
Zeitschrift fuer Chemie (Stuttgart, Germany), , vol. 25, # 12 p. 431
反应条件
tin(ll) chloride in ethanol 5 h; Heating;
参考文献
Lippmann, Eberhard; Burckhardt, Helmut
Zeitschrift fuer Chemie (Stuttgart, Germany), 1985 , vol. 25, # 12 p. 431
反应条件
1: 86 percent / POCl3, N,N-dimethylaniline / 2 h / Heating
2: 100 percent / hydrazine hydrate / ethanol / 1 h / Ambient temperature
3: 63 percent / lead dioxide / H2O; toluene / 15 h
4: hydroxylamine hydrochloride, KOH / ethanol; methanol / 1.) 0 deg C, 30 min; 2.) r.t., 1 h
5: 21 percent / 98percent hydrazine hydrate / 10percent Pd/C / ethanol / 2 h / 65 °C
View Scheme
参考文献
Nasielski, J.; Nasielski-Hinkens, R.; Heilporn, S.; Rypens, C.; Declercq, J. P.
Bulletin des Societes Chimiques Belges, 1988 , vol. 97, # 11-12 p. 983 - 992
