potassium hydroxide in tetrahydrofuran; water 1 h; Reflux;

1: potassium hydroxide / water; tetrahydrofuran / 1 h / |Reflux 2: palladium 10 on activated carbon; hydrogen / ethyl acetate / 12 h / 20 °C View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '22797635', constants.ctx, '0')">C₁₆H₁₄N₂O₄Pd</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3595636', constants.ctx, '0')">silver(I) acetate</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '106420', constants.ctx, '0')">1-methyl-pyrrolidin-2-one</a> <br />T=90&deg;C;&nbsp;6&nbsp;h;&nbsp;<br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '4153970', constants.ctx, '0')">sodium hydrogencarbonate</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '610776', constants.ctx, '0')">triphenylphosphine</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a> <br />T=20&deg;C;&nbsp;Wittig Olefination;&nbsp;2&nbsp;h;&nbsp;<br /> &nbsp;

&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a> <br />24&nbsp;h;&nbsp;&nbsp;Reflux;&nbsp;<br /> &nbsp;