1-(3,4-二氯苯基)-吡咯-2,5-二酮合成路线 （共 6 条）
反应条件
sodium acetate in acetic anhydride T=20 - 100°C; 0.5 h;
参考文献
Budke, Brian; Kalin, Jay H.; Pawlowski, Michal; Zelivianskaia, Anna S.; Wu, Megan; Kozikowski, Alan P.; Connell, Philip P.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 1 p. 254 - 263
反应条件
sodium acetate; acetic anhydride T=75°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 5 p. 1510 - 1515
反应条件
1: diethyl ether / 2 h / 20 °C 2: sodium acetate / acetic anhydride / 0.5 h / 20 - 100 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 56, # 1 p. 254 - 263
反应条件
dirhodium tetraacetate Heating; Further byproducts given;
参考文献
Lu, Chong-Dao; Chen, Zhi-Yong; Liu, Hui; Hu, Wen-Hao; Mi, Ai-Qiao; Doyle, Michael P.
Journal of Organic Chemistry, 2004 , vol. 69, # 14 p. 4856 - 4859
反应条件
dirhodium tetraacetate
Heating; Further byproducts given;
参考文献
Lu, Chong-Dao; Chen, Zhi-Yong; Liu, Hui; Hu, Wen-Hao; Mi, Ai-Qiao; Doyle, Michael P.
Journal of Organic Chemistry, 2004 , vol. 69, # 14 p. 4856 - 4859
反应条件
pyridine; thionyl chloride
T=0°C; 1.25 h; Reflux;
参考文献
Budke, Brian; Kalin, Jay H.; Pawlowski, Michal; Zelivianskaia, Anna S.; Wu, Megan; Kozikowski, Alan P.; Connell, Philip P.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 1 p. 254 - 263
