4-(2-吡嗪基)-2-氨基噻唑合成路线 (共 2 条)
反应条件
N-ethyl-N,N-diisopropylamine in ethanol; water 3 h; Inert atmosphereReflux;
参考文献
Meissner, Anja; Boshoff, Helena I.; Vasan, Mahalakshmi; Duckworth, Benjamin P.; Barry III, Clifton E.; Aldrich, Courtney C.
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 21 p. 6385 - 6397
反应条件
1: bromine; acetic acid; hydrogen bromide / 4 h / 23 °C / |Inert atmosphere 2: N-ethyl-N,N-diisopropylamine / ethanol; water / 3 h / |Inert atmosphere; |Reflux View Scheme
参考文献
Meissner, Anja; Boshoff, Helena I.; Vasan, Mahalakshmi; Duckworth, Benjamin P.; Barry III, Clifton E.; Aldrich, Courtney C.
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 21 p. 6385 - 6397