您好，欢迎来到魔法化学网！
合作交流
|
服务时间(9:30-18:00)
百科
百科
▼
百科
资讯
搜索
结构式
乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
首页
化合物百科
价格行情
资讯
化工导航
实验室工具
搜索
乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
198479-82-2
合成路线
（共 11 条）
80494-75-3
(4-氯甲基苯氧基)-乙酸乙酯
+
198479-63-9
3-甲基-5-苄氧基-2-(4-苄氧基苯基)-1H-吲哚
→
反应条件
198479-82-2
反应条件
1: 5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole With sodium hydride in N,N-dimethyl-formamide T=0°C; 0.333333 h; 2: ethyl [p-(chloromethyl)phenoxy]acetate in N,N-dimethyl-formamide T=20°C; 18 h; Further stages.;
参考文献
Miller; Collini; Tran; Harris; Kharode; Marzolf; Moran; Henderson; Bender; Unwalla; Greenberger; Yardley; Abou-Gharbia; Lyttle; Komm
Journal of Medicinal Chemistry, 2001 , vol. 44, # 11 p. 1654 - 1657
198479-63-9
3-甲基-5-苄氧基-2-(4-苄氧基苯基)-1H-吲哚
→
反应条件
198479-82-2
反应条件
in ethyl acetate; N,N-dimethyl-formamide
参考文献
Wyeth
Patent: EP1076558 B1, 2003 ;
623-05-2
对羟基苯甲醇
→
反应条件
198479-82-2
反应条件
1.1: K2CO3 2.1: SOCl2 / tetrahydrofuran 3.1: sodium hydride / dimethylformamide / 0.33 h / 0 °C 3.2: 59 percent / dimethylformamide / 18 h / 20 °C View Scheme
参考文献
Lusin, Tina Trdan; Tomasic, Tihomir; Trontelj, Jurij; Mrhar, Ales; Peterlin-Masic, Lucija
Chemico-Biological Interactions, 2012 , vol. 197, # 1 p. 8 - 15
35081-45-9
4’-苯甲氧基-2-溴苯丙酮
→
反应条件
198479-82-2
反应条件
1.1: 51 percent / Et3N / dimethylformamide / Heating 2.1: sodium hydride / dimethylformamide / 0.33 h / 0 °C 2.2: 59 percent / dimethylformamide / 18 h / 20 °C View Scheme
参考文献
Lusin, Tina Trdan; Tomasic, Tihomir; Trontelj, Jurij; Mrhar, Ales; Peterlin-Masic, Lucija
Chemico-Biological Interactions, 2012 , vol. 197, # 1 p. 8 - 15
103258-64-6
2-(4-(羟基甲基)苯氧基)乙酸乙酯
→
反应条件
198479-82-2
反应条件
1.1: SOCl2 / tetrahydrofuran 2.1: sodium hydride / dimethylformamide / 0.33 h / 0 °C 2.2: 59 percent / dimethylformamide / 18 h / 20 °C View Scheme
参考文献
Lusin, Tina Trdan; Tomasic, Tihomir; Trontelj, Jurij; Mrhar, Ales; Peterlin-Masic, Lucija
Chemico-Biological Interactions, 2012 , vol. 197, # 1 p. 8 - 15
51388-20-6
4-苯甲氧基苯胺盐酸盐
→
反应条件
198479-82-2
反应条件
1.1: 51 percent / Et3N / dimethylformamide / Heating 2.1: sodium hydride / dimethylformamide / 0.33 h / 0 °C 2.2: 59 percent / dimethylformamide / 18 h / 20 °C View Scheme
参考文献
Miller; Collini; Tran; Harris; Kharode; Marzolf; Moran; Henderson; Bender; Unwalla; Greenberger; Yardley; Abou-Gharbia; Lyttle; Komm
Journal of Medicinal Chemistry, 2001 , vol. 44, # 11 p. 1654 - 1657
4495-66-3
→
反应条件
198479-82-2
反应条件
1.1: bromine / acetic acid / 3 h / 0 - 20 °C 2.1: triethylamine / N,N-dimethyl-formamide / 4 h / 120 - 150 °C / Inert atmosphere 3.1: sodium hydride / N,N-dimethyl-formamide / 0.33 h / 0 °C 3.2: 20 °C View Scheme
参考文献
Lusin, Tina Trdan; Tomasic, Tihomir; Trontelj, Jurij; Mrhar, Ales; Peterlin-Masic, Lucija
Chemico-Biological Interactions, 2012 , vol. 197, # 1 p. 8 - 15
100-39-0
溴化苄
→
反应条件
198479-82-2
反应条件
1.1: potassium carbonate / acetone / 60 °C 2.1: bromine / acetic acid / 3 h / 0 - 20 °C 3.1: triethylamine / N,N-dimethyl-formamide / 4 h / 120 - 150 °C / Inert atmosphere 4.1: sodium hydride / N,N-dimethyl-formamide / 0.33 h / 0 °C 4.2: 20 °C View Scheme
参考文献
Lusin, Tina Trdan; Tomasic, Tihomir; Trontelj, Jurij; Mrhar, Ales; Peterlin-Masic, Lucija
Chemico-Biological Interactions, 2012 , vol. 197, # 1 p. 8 - 15
70-70-2
对羟基苯丙酮
→
反应条件
198479-82-2
反应条件
1.1: potassium carbonate / acetone / 60 °C 2.1: bromine / acetic acid / 3 h / 0 - 20 °C 3.1: triethylamine / N,N-dimethyl-formamide / 4 h / 120 - 150 °C / Inert atmosphere 4.1: sodium hydride / N,N-dimethyl-formamide / 0.33 h / 0 °C 4.2: 20 °C View Scheme
参考文献
Lusin, Tina Trdan; Tomasic, Tihomir; Trontelj, Jurij; Mrhar, Ales; Peterlin-Masic, Lucija
Chemico-Biological Interactions, 2012 , vol. 197, # 1 p. 8 - 15
198479-82-2
→
反应条件
198481-32-2
1-[[4-[2-(氮杂环庚烷-1-基)乙氧基]苯基]甲基]-2-(4-羟基苯基)-3-甲基-吲哚-5-醇
反应条件
1: 78 percent / LiAlH4 / tetrahydrofuran / 0.5 h / 0 °C 2: 87 percent / CBr4; Ph3P / tetrahydrofuran / 3 h / 20 °C 3: tetrahydrofuran 4: H2 / Pd/C / ethanol; tetrahydrofuran / 20 °C View Scheme
参考文献
Lusin, Tina Trdan; Tomasic, Tihomir; Trontelj, Jurij; Mrhar, Ales; Peterlin-Masic, Lucija
Chemico-Biological Interactions, 2012 , vol. 197, # 1 p. 8 - 15
1
2
下一页
末页
到第
页
确定
