N-(叔丁氧羰基)-2-硝基苯酰胺合成路线 （共 16 条）
反应条件
1: potassium carbonate / N,N-dimethyl-formamide; toluene / 2 h / 20 °C / |Inert atmosphere
2: trifluoroacetic acid / dichloromethane / 12 h / 20 °C / |Inert atmosphere
3: N1-(2-Amino-ethyl)-ethane-1,2-diamine; hydrogen / methanol / 4 h / 25 °C
View Scheme
参考文献
Kawanishi, Akinori; Miyamoto, Chiyako; Yabe, Yuki; Inai, Makoto; Asakawa, Tomohiro; Hamashima, Yoshitaka; Sajiki, Hironao; Kan, Toshiyuki
Organic Letters, 2013 , vol. 15, # 6 p. 1306 - 1309
反应条件
1: potassium carbonate / N,N-dimethyl-formamide; toluene / 2 h / 20 °C / |Inert atmosphere
2: trifluoroacetic acid / dichloromethane / 12 h / 20 °C / |Inert atmosphere
3: hydrogen / methanol / 2 h / 25 °C
View Scheme
参考文献
Kawanishi, Akinori; Miyamoto, Chiyako; Yabe, Yuki; Inai, Makoto; Asakawa, Tomohiro; Hamashima, Yoshitaka; Sajiki, Hironao; Kan, Toshiyuki
Organic Letters, 2013 , vol. 15, # 6 p. 1306 - 1309
反应条件
1: DMEAD; triphenylphosphine / toluene / 12 h / 20 °C / |Inert atmosphere
2: trifluoroacetic acid / dichloromethane / 12 h / 20 °C / |Inert atmosphere
3: hydrogen / methanol / 10 h / 25 °C
View Scheme
参考文献
Kawanishi, Akinori; Miyamoto, Chiyako; Yabe, Yuki; Inai, Makoto; Asakawa, Tomohiro; Hamashima, Yoshitaka; Sajiki, Hironao; Kan, Toshiyuki
Organic Letters, 2013 , vol. 15, # 6 p. 1306 - 1309
反应条件
1: 95 percent / K2CO3 / dimethylformamide / 0.33 h / 20 °C
2: 100 percent / TFA / 0.08 h / 23 °C
View Scheme
参考文献
Fukuyama, Tohru; Cheung, Mui; Kan, Toshiyuki
Synlett, 1999 , # 8 p. 1301 - 1303
反应条件
1: 95 percent / K2CO3 / dimethylformamide / 0.33 h / 20 °C
2: 92 percent / LiOH*H2O; mercaptoacetic acid / dimethylformamide / 0.42 h / 23 °C
View Scheme
参考文献
Fukuyama, Tohru; Cheung, Mui; Kan, Toshiyuki
Synlett, 1999 , # 8 p. 1301 - 1303
反应条件
diethylazodicarboxylate in toluene; benzene
T=0 - 20°C; Inert atmosphere;
参考文献
Fujii, Masaya; Nishimura, Takuya; Koshiba, Takahiro; Yokoshima, Satoshi; Fukuyama, Tohru
Organic Letters, 2013 , vol. 15, # 1 p. 232 - 234
