(4-羟基-3,5-二甲基苯基)乙酸合成路线 （共 3 条）
反应条件
1: With potassium hydroxide; water in ethylene glycol dimethyl ether 48 h; Heating / reflux; 2: With hydrogenchloride in water pH=2;
参考文献
F. HOFFMANN-LA ROCHE AG
Patent: WO2007/9913 A1, 2007 ;
Location in patent: Page/Page column 62-63 ;
WO 2007/009913 A1
反应条件
tetrabutylammomium bromide; hydrogen bromide in dichloromethane 24 h; Heating;
参考文献
Bhalerao; Raju; Neelakantan
Synthetic Communications, 1995 , vol. 25, # 10 p. 1433 - 1439
反应条件
ethanol Erhitzen des Reaktionsprodukts mit wss. KOH in Aethylenglykol;
参考文献
Gardner et al.
Journal of the American Chemical Society, 1959 , vol. 81, p. 3364
