4-(1,3-噻唑-2-基)苯甲醛合成路线 (共 4 条)
反应条件
sodium carbonate; tetrakis (triphenylphosphine) palladium (0) in ethanol; water; toluene
参考文献
Takeda Chemical Industries, Ltd.
Patent: EP1123918 A1, 2001 ;
反应条件
hydrogenchloride; [1,3-bis(diphenylphosphino) propane] dichloronickel(II); iodine; diisobutylaluminium hydride; magnesium Yield given. Multistep reaction;
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 18 p. 3387 - 3401
反应条件
hydrogenchloride in tetrahydrofuran; diethyl ether; hexane; water
反应条件
sodium tetrahydroborate; ethanol in tetrahydrofuran T=20°C; 1.5 h;
参考文献
EP2264009 A1, ;
Page/Page column 101 ;