[[4-(2-吡啶基)苯基]亚甲基]-肼羧酸叔丁酯合成路线 （共 12 条）
反应条件
palladium monocarbide in n-heptane; hydrogen
反应条件
1: palladium 10 on activated carbon; sodium formate / water; ethanol / 1.5 h / 57 °C 2: isopropyl alcohol / 24 h / |Inert atmosphere; |Reflux; |Large scale 3: hydrogenchloride / tetrahydrofuran / 3 h / 22 - 55 °C / |Large scale 4: N-ethyl-N,N-diisopropylamine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 22 - 25 °C / |Large scale View Scheme
参考文献
Xu, Zhongmin; Singh, Janak; Schwinden, Mark D.; Zheng, Bin; Kissick, Thomas P.; Patel, Bharat; Humora, Michael J.; Quiroz, Fernando; Dong, Lin; Hsieh, Dau-Ming; Heikes, James E.; Pudipeddi, Madhusudhan; Lindrud, Mark D.; Srivastava, Sushil K.; Kronenthal, David R.; Mueller, Richard H.
Organic Process Research and Development, 2002 , vol. 6, # 3 p. 323 - 328
