hydrogen; palladium on activated charcoal in ethanol P=760 Torr; Ambient temperature;

1: 98 percent / H2 / 10percent Pd/C / ethanol / 760 Torr / Ambient temperature 2: 1.) 2,2,6,6-tetramethylpiperidine, n-butyllithium / 1.) THF, from -78 deg C to RT, 30 min, 2.) THF, -78 deg C, 1 h 3: 1.) lithium 2,2,6,6-tetramethylpiperidide, hexamethylphosphoric triamide / 1.) THF, from -78 deg C to RT, 2.) THF, room temp., 30 min 4: 100 percent / acetic acid, 30percent H2O2 / tetrahydrofuran / 0.5 h / 0 °C View Scheme