1,2:4,5-双-O-(异亚丙基)-β-L-赤式-2,3-二酮-2,6-吡喃糖合成路线 （共 5 条）
反应条件
sodium periodate; RuCl3 monohydrate; N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate in chloroform T=1.5°C; Reflux;
参考文献
MASSACHUSSETS INSTITUTE OF TECHNOLOGY; JAMISON, Timothy, F.; IKEUCHI, Yutaka
Patent: WO2011/109276 A1, 2011 ;
Location in patent: Page/Page column 24-25; 1/2 ;
反应条件
1.1: 300.8 g / pyridine / 2 h / 0 °C 2.1: aq. H2SO4 / 3 h / 20 °C 2.2: aq. NaOH / 8 h / 90 - 100 °C 2.3: aq. H2SO4 / 0.5 h / 70 - 80 °C 3.1: 32.5 g / aq. H2SO4 / acetone / 6 h / 0 °C 4.1: 87 percent / PDC; 3 Angstroem molecular sieves; AcOH / CH2Cl2 / 20 °C View Scheme
参考文献
Wang, Zhi-Xian; Tu, Yong; Frohn, Michael; Zhang, Jian-Rong; Shi, Yian
Journal of the American Chemical Society, 1997 , vol. 119, # 46 p. 11224 - 11235
反应条件
1: 32.5 g / aq. H2SO4 / acetone / 6 h / 0 °C 2: 87 percent / PDC; 3 Angstroem molecular sieves; AcOH / CH2Cl2 / 20 °C View Scheme
参考文献
Wang, Zhi-Xian; Tu, Yong; Frohn, Michael; Zhang, Jian-Rong; Shi, Yian
Journal of the American Chemical Society, 1997 , vol. 119, # 46 p. 11224 - 11235
反应条件
1.1: aq. H2SO4 / 3 h / 20 °C 1.2: aq. NaOH / 8 h / 90 - 100 °C 1.3: aq. H2SO4 / 0.5 h / 70 - 80 °C 2.1: 32.5 g / aq. H2SO4 / acetone / 6 h / 0 °C 3.1: 87 percent / PDC; 3 Angstroem molecular sieves; AcOH / CH2Cl2 / 20 °C View Scheme
参考文献
Wang, Zhi-Xian; Tu, Yong; Frohn, Michael; Zhang, Jian-Rong; Shi, Yian
Journal of the American Chemical Society, 1997 , vol. 119, # 46 p. 11224 - 11235
参考文献
Shi, Yian
Patent: US6348608 B1, 2002 ;
Location in patent: Page column 26 ;
