2,3,3-三甲基-丁酸甲酯合成路线 （共 13 条）
反应条件
1: 3,3-dimethylbutyric acid methyl ester With lithium diisopropyl amide in tetrahydrofuran T=-78°C; 1 h; 2: methyl iodide in tetrahydrofuran T=-78 - 20°C; 4 h; Further stages.;
参考文献
Hoffmann, Sebastian; Nicoletti, Marcello; List, Benjamin
Journal of the American Chemical Society, 2006 , vol. 128, # 40 p. 13074 - 13075
反应条件
zinc(II) chloride in dichloromethane Ambient temperature;
参考文献
Reetz, Manfred T.; Schwellnus, Konrad; Huebner, Friedhelm; Massa, Werner; Schmidt, Roland E.
Chemische Berichte, 1983 , vol. 116, # 11 p. 3708 - 3724
参考文献
Saunders,W.H.; Carges,G.L.
Journal of the American Chemical Society, 1960 , vol. 82, p. 3582 - 3585
反应条件
1: dioxane; diethyl ether; bromine 2: diethyl ether View Scheme
参考文献
Sarel; Newman
Journal of the American Chemical Society, 1956 , vol. 78, p. 5416,5418
反应条件
lithium diisopropyl amide
参考文献
Angelaud, Remy; Landais, Yannick
Tetrahedron Letters, 1997 , vol. 38, # 2 p. 233 - 236
反应条件
methanol; Pd-BaSO4 Hydrogenation;
参考文献
Crawford; Swift
Journal of the Chemical Society, 1952 , p. 1220,1222
反应条件
Yield given. Multistep reaction;
参考文献
Arjona, Odon; Perez-Ossorio, Rafael; Perez-Rubalcaba, Alfredo; Quiroga, Maria L.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1981 , p. 597 - 603
反应条件
1: NaOH / bis-(2-hydroxy-ethyl) ether 2: PhCOCl 3: (i) Mg, Et2O, CdCl2, (ii) /BRN= 1747009/ 4: LiAlH4 View Scheme
参考文献
Saunders,W.H.; Carges,G.L.
Journal of the American Chemical Society, 1960 , vol. 82, p. 3582 - 3585
反应条件
sodium hydroxide in diethylene glycol
参考文献
Saunders,W.H.; Carges,G.L.
Journal of the American Chemical Society, 1960 , vol. 82, p. 3582 - 3585
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
参考文献
Arjona, Odon; Perez-Ossorio, Rafael; Perez-Rubalcaba, Alfredo; Quiroga, Maria L.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1981 , p. 597 - 603
