(S)-1-Boc-3-氨甲基吡咯烷合成路线 （共 4 条）
反应条件
hydrogen in ethanol; water P=3102.97 Torr;
参考文献
GLAXOSMITHKLINE LLC; DOCK, Steven, Thomas; MCSHERRY, Allison, K.; MOORE, Michael, Lee; RIDGERS, Lance, Howard; PARRISH, Cynthia, Ann
Patent: WO2013/28445 A1, 2013 ;
Location in patent: Page/Page column 51; 52 ;
反应条件
sodium hydrogencarbonate in hexane; acetonitrile
参考文献
US6166015 A1, ;
US 6166015 A
反应条件
1: triethylamine / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere 2: N,N-dimethyl-formamide / 100 °C / Inert atmosphere 3: triethylamine; hydrogen / ethanol / 20 °C / 2585.81 - 3102.97 Torr / Inert atmosphere View Scheme
参考文献
WO2012/37298 A1, ;
WO 2012/037298 A1
反应条件
1: N,N-dimethyl-formamide / 100 °C / Inert atmosphere 2: triethylamine; hydrogen / ethanol / 20 °C / 2585.81 - 3102.97 Torr / Inert atmosphere View Scheme
参考文献
WO2012/37298 A1, ;
WO 2012/037298 A1
