1: NaNH2; toluene
2: diethyl ether; toluene / und Behandeln des Reaktionsgemisches mit Eis und wss.Salzsaeure
3: concentrated hydrobromic acid; water
View Scheme
1: 1) NaH / 1) paraffin oil; 2) reflux, 10 min
2: 44 percent / sulphuric acid (50percent) / 0.5 h / 120 - 130 °C
3: 78 percent / boron tribromide / CH2Cl2 / 1 h at -70 deg C, then within 2 h to room temp.
View Scheme
参考文献
Murphy, William S.; Wattanasin, Sompong
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1555 - 1566
