2-(Boc-氨基)吡啶-5-甲醛合成路线 (共 5 条)
反应条件
N,N,N',N,-tetramethylethylenediamine; hydrogen; di-(1-adamantyl)-n-butylphosphine; palladium diacetate in tetrahydrofuran T=100°C; P=3750.38 Torr; 16 h;
参考文献
SANOFI; BOEHM, Claudius; KLEIN, Susanne; NAPIERSKI, Bernard; SOMMER, Christian
Patent: US2013/245274 A1, 2013 ;
Location in patent: Paragraph 0283; 0284 ;
反应条件
diisobutylaluminium hydride; triethylamine in hexane; dichloromethane; water; dimethyl sulfoxide
参考文献
US5866573 A1, ;
US 5866573 A
反应条件
pyridine-SO3 complex; dimethyl sulfoxide; triethylamine T=20°C;
参考文献
EP2216330 A1, ;
Page/Page column 24 ;
EP 2216330 A1
反应条件
1: LiAlH4 View Scheme
参考文献
Nantermet, Philippe G.; Barrow, James C.; Lindsley, Stacey R.; Young, Marybeth; Mao, Shi-Shan; Carroll, Steven; Bailey, Carolyn; Bosserman, Michele; Colussi, Dennis; McMasters, Daniel R.; Vacca, Joseph P.; Selnick, Harold G.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 9 p. 2141 - 2145
反应条件
lithium aluminium tetrahydride
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 9 p. 2141 - 2145