7-甲氧基-6-(3-吗啉-4-基丙氧基)喹唑啉-4(3H)-酮合成路线 （共 22 条）
反应条件
1: 7-methoxy-6-(3-morpholinopropoxy)-3,4-dihydroquinazolin-4-one With thionyl chloride in N,N-dimethyl-formamide 2 h; Heating; 2: para-fluoro-meta-chloroaniline in N,N-dimethyl-formamide T=100°C; 1 h; Further stages.;
参考文献
Chandregowda, Venkateshappa; Venkateswara Rao, Gudapati; Chandrasekara Reddy, Goukanapalli
Heterocycles, 2007 , vol. 71, # 1 p. 39 - 48
反应条件
1.1: P2S5 / pyridine / 24 h / Heating 2.1: aq. NaOH / methanol / 15 - 20 °C 2.2: 8.3 g / methanol; H2O / 5 h / 20 °C 3.1: 85 percent / 3-chloro-4-fluoroaniline hydrochloride / propan-2-ol / 24 h / Heating View Scheme
参考文献
Seimbille, Yann; Phelps, Michael E.; Czernin, Johannes; Silverman, Daniel H. S.
Journal of Labelled Compounds and Radiopharmaceuticals, 2005 , vol. 48, # 11 p. 829 - 843
