4'-(三氟甲基)双苯基-3-羧酸合成路线 （共 2 条）
反应条件
5 Pd(II)/C(eggshell); sodium carbonate in water; isopropyl alcohol T=75°C; 3 h; Large scale reaction;
参考文献
Walker, Shawn D.; Borths, Christopher J.; Divirgilio, Evan; Huang, Liang; Liu, Pingli; Morrison, Henry; Sugi, Kiyoshi; Tanaka, Masahide; Woo, Jacqueline C. S.; Faul, Margaret M.
Organic Process Research and Development, 2011 , vol. 15, # 3 p. 570 - 580
反应条件
1: sodium tetrahydroborate; boron trifluoride-tetrahydrofuran complex; boric acid trimethyl ester / tetrahydrofuran / 4 h / 41 - 49 °C / Large scale reaction
2: thionyl bromide; triethylamine / toluene / 2.8 h / 35 - 40 °C / Large scale reaction
View Scheme
参考文献
Walker, Shawn D.; Borths, Christopher J.; Divirgilio, Evan; Huang, Liang; Liu, Pingli; Morrison, Henry; Sugi, Kiyoshi; Tanaka, Masahide; Woo, Jacqueline C. S.; Faul, Margaret M.
Organic Process Research and Development, 2011 , vol. 15, # 3 p. 570 - 580
