1: 1-bromo-4-chloro-2-fluoro-benzene With lithium diisopropyl amide in tetrahydrofuran
T=-50 - -20°C;
2: N,N-dimethyl-formamide in tetrahydrofuran
T=-50°C;
参考文献
Balko, Terry W.; Schmitzer, Paul R.; Daeuble, John F.; Yerkes, Carla N.; Siddall, Thomas L.
Patent: US2007/179060 A1, 2007 ;
Location in patent: Page/Page column 8-9 ;
