potassium carbonate in ethanol; water 1 h; Heating / reflux;

1: 1.) aq. HCl, aq. NaNO2, 2.) aq. KI / 1.) 30 min, 2.) CHCl3, RT, 7 h 2: 78 percent / CuI, KF / dimethylformamide / 8 h / Heating 3: 67 percent / 3 N HCl / ethanol / 4 h / Heating View Scheme

1: 78 percent / CuI, KF / dimethylformamide / 8 h / Heating 2: 67 percent / 3 N HCl / ethanol / 4 h / Heating View Scheme

暂无反应条件数据

1: 83 percent / CuBr, NaOMe / 24 h / 70 °C 2: NaOH / methanol; H2O / 3 h / Ambient temperature 3: ethyl acetate / 6 h / 65 °C 4: 1.34 g / LiAlH4 / tetrahydrofuran / 16 h / Heating 5: Et3N / CH2Cl2 / 0.5 h / below 0 deg C 6: NH3 / tetrahydrofuran / 60 h / -78 - 24 °C / 6205.8 Torr View Scheme

1: Et3N / CH2Cl2 / 0.5 h / below 0 deg C 2: NH3 / tetrahydrofuran / 60 h / -78 - 24 °C / 6205.8 Torr View Scheme

1: 1.34 g / LiAlH4 / tetrahydrofuran / 16 h / Heating 2: Et3N / CH2Cl2 / 0.5 h / below 0 deg C 3: NH3 / tetrahydrofuran / 60 h / -78 - 24 °C / 6205.8 Torr View Scheme

1: NaOH / methanol; H2O / 3 h / Ambient temperature 2: ethyl acetate / 6 h / 65 °C 3: 1.34 g / LiAlH4 / tetrahydrofuran / 16 h / Heating 4: Et3N / CH2Cl2 / 0.5 h / below 0 deg C 5: NH3 / tetrahydrofuran / 60 h / -78 - 24 °C / 6205.8 Torr View Scheme