1: 95 percent / Ba(OH)2 / Pd(0) 2: 70 percent / 1.) LDA; 2.) 50percent aq. HOAc / 1.) THF, reflux, 2.5 h; 2.) reflux, 10 min 3: 81 percent / Et3N / CH2Cl2 / -78 °C 4: 69 percent / LiCl, (2-furyl)3P / Pd2(dba)3 / various solvent(s) / 5 h / Ambient temperature 5: 90 percent / BCl3 / CH2Cl2 / 0.17 h / 0 °C View Scheme

<b>Multi-step reaction with 3 steps<br /> </b>1: N-iodo-succinimide / N,N-dimethyl-formamide / 20 &deg;C<br />2: potassium carbonate / N,N-dimethyl-formamide / 1.5 h / 50 &deg;C<br />3: potassium acetate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct / dimethyl sulfoxide / 2.5 h / 80 &deg;C<br /> <br /> &nbsp;