1: 70 percent / 1.) LDA; 2.) 50percent aq. HOAc / 1.) THF, reflux, 2.5 h; 2.) reflux, 10 min 2: 81 percent / Et3N / CH2Cl2 / -78 °C 3: 69 percent / LiCl, (2-furyl)3P / Pd2(dba)3 / various solvent(s) / 5 h / Ambient temperature 4: 90 percent / BCl3 / CH2Cl2 / 0.17 h / 0 °C View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11604118', constants.ctx, '0')">tetrakis(triphenylphosphine) palladium⁽⁰⁾</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '14227090', constants.ctx, '0')">Ba(OH)₂*8H₂O</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1209237', constants.ctx, '0')">ethylene glycol dimethyl ether</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a> <br />Suzuki coupling;&nbsp;3&nbsp;h;&nbsp;&nbsp;Inert atmosphereReflux;&nbsp;<br /> &nbsp;