6,7-二氢苯并[B]噻吩-4(5H)-酮肟合成路线 （共 14 条）
反应条件
hydroxylamine hydrochloride; sodium acetate in ethanol Condensation;
参考文献
Albright, J. Donald; Santos, Efren G. Delos; Dusza, John P.; Chan, Peter S.; Coupet, Joseph; Ru, Xun; Mazandarani
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 8 p. 695 - 698
反应条件
hydroxylamine hydrochloride; sodium acetate in ethanol; water
反应条件
1: thionyl chloride; pyridine; diethyl ether 2: aluminium chloride 3: hydroxylamine View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 62,68, 713, 717
反应条件
1: aluminium chloride 2: hydroxylamine View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 62,68, 713, 717
反应条件
1: hydrazine hydrate; potassium hydroxide; diethylene glycol 2: thionyl chloride; pyridine; diethyl ether 3: aluminium chloride 4: hydroxylamine View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 62,68, 713, 717
反应条件
P2O5; methanesulfonic acid T=100 - 110°C; 5 h;
参考文献
Royer,R. et al.
European Journal of Medicinal Chemistry, 1976 , vol. 11, p. 221 - 224
参考文献
Albright, J. Donald; Santos, Efren G. Delos; Dusza, John P.; Chan, Peter S.; Coupet, Joseph; Ru, Xun; Mazandarani
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 8 p. 695 - 698
反应条件
diisobutylaluminium hydride in dichloromethane T=25°C; 2 h;
参考文献
Cho, Hidetsura; Murakami, Kengo; Nakanishi, Hiroyuki; Isoshima, Hirotaka; Hayakawa, Kazuhide; Uchida, Itsuo
Heterocycles, 1998 , vol. 48, # 5 p. 919 - 927
反应条件
aluminum dichloride hydride in CPME T=0 - 20°C; 3 h;
参考文献
Cho, Hidetsura; Iwama, Yusuke; Mitsuhashi, Nakako; Sugimoto, Kenji; Okano, Kentaro; Tokuyama, Hidetoshi
Molecules, 2012 , vol. 17, # 6 p. 7348 - 7355
反应条件
diisobutylaluminium hydride in dichloromethane T=25°C; 2 h;
参考文献
Cho, Hidetsura; Murakami, Kengo; Nakanishi, Hiroyuki; Isoshima, Hirotaka; Hayakawa, Kazuhide; Uchida, Itsuo
Heterocycles, 1998 , vol. 48, # 5 p. 919 - 927
