2,2,2-三氯-1-苯基乙醇合成路线 （共 82 条）
反应条件
trichloroacetic acid in N,N-dimethyl-formamide T=5 - 20°C; 17.5 h;
参考文献
Perryman, Michael S.; Harris, Matthew E.; Foster, Jade L.; Joshi, Anushka; Clarkson, Guy J.; Fox, David J.
Chemical Communications, 2013 , vol. 49, # 85 p. 10022 - 10024
反应条件
potassium hydroxide in methanol; N,N-dimethyl-formamide T=-8°C; 2 h;
参考文献
Wyvratt, Jean M.; Hazen, George G.; Weinstock, Leonard M.
Journal of Organic Chemistry, 1987 , vol. 52, # 5 p. 944 - 945
反应条件
sodium formate in N,N-dimethyl-formamide T=20°C; 1 h; Further stages.;
参考文献
Kister, Jeremy; Mioskowski, Charles
Journal of Organic Chemistry, 2007 , vol. 72, # 10 p. 3925 - 3928
反应条件
lead(II) bromide; aluminium in N,N-dimethyl-formamide 3.5 h; Ambient temperature;
参考文献
Tanaka, Hideo; Yamashita, Shiro; Yamanoue, Motoi; Torii, Sigeru
Journal of Organic Chemistry, 1989 , vol. 54, # 2 p. 444 - 450
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in diethyl ether T=40 - 45°C; 2 h;
参考文献
Volkov, Yu. P.; Yanovskaya, L. A.; Kryshtal', G. V.; Kalinevich, V. M.; Trusova, E. I.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1986 , vol. 35, # 6 p. 1242 - 1245
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1986 , # 6 p. 1368 - 1372
反应条件
trichloroacetic acid sodium salt in N,N-dimethyl-formamide T=25 - 35°C; Decarboxylation; addition;
参考文献
Wang, Zhe; Campagna, Silvio; Yang, Kaihong; Xu, Guoyou; Pierce, Michael E.; Fortunak, Joseph M.; Confalone, Pat N.
Journal of Organic Chemistry, 2000 , vol. 65, # 6 p. 1889 - 1891
反应条件
aluminium trichloride T=-10 - 0°C; 12 h;
参考文献
Menegheli, Paulo; Rezende, Marcos Caroli; Zucco, Cezar
Synthetic Communications, 1987 , vol. 17, # 4 p. 457 - 464
反应条件
1: T=0°C; 0.5 h; 2: With N-iodo-succinimide T=20°C; 1 h; Reagent/catalyst;
参考文献
Dohi, Souya; Moriyama, Katsuhiko; Togo, Hideo
European Journal of Organic Chemistry, 2013 , # 34 p. 7815 - 7822
反应条件
1: T=0°C; 0.5 h; 2: With tert-butylhypochlorite; potassium iodide T=20°C; 4 h; Reagent/catalyst;
参考文献
European Journal of Organic Chemistry, , # 34 p. 7815 - 7822
反应条件
isopropylmagnesium chloride in tetrahydrofuran T=-78°C;
参考文献
Bulletin de la Societe Chimique de France, , p. 1189 - 1192
