4'-甲氧基-2-硝基联苯合成路线 （共 37 条）
反应条件
K3PO4*3H2O; (2-mesityl-1H-inden-3-yl)dicyclohexylphosphine; palladium diacetate; Aliquatreg; 336 in water T=20 - 100°C; Suzuki-Miyaura Coupling; 8 h; Inert atmosphere;
参考文献
Mao, Shu-Lan; Sun, Yue; Yu, Guang-Ao; Zhao, Cui; Han, Zhi-Jun; Yuan, Jia; Zhu, Xiaolei; Yang, Qihua; Liu, Sheng-Hua
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 47 p. 9410 - 9417
反应条件
potassium carbonate; tetrakis(triphenylphosphine) palladium(0) in water; toluene 48 h; Heating / reflux;
参考文献
Koninklijke Philips Electronics N.V.
Patent: EP1838671 B1, 2008 ;
Location in patent: Page/Page column 11 ;
反应条件
bis(η3-allyl-μ-chloropalladium(II)); triphenyl-arsane; caesium carbonate in 1,4-dioxane T=90°C; 24 h;
参考文献
Denmark, Scott E.; Ober, Michael H.
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 13-15 p. 1703 - 1714
反应条件
2,2'-bis(di-p-tolyl-phosphino)-1,1'-binaphthyl; copper(I) oxide; 1,10-phenanthroline; palladium (II) 2,4-pentanedionate in 1-methyl-pyrrolidin-2-one T=50 - 190°C; P=3375.34 Torr; Inert atmosphereMicrowave irradiation;
参考文献
Goossen, Lukas J.; Linder, Christophe; Rodriguez, Nuria; Lange, Paul P.
Chemistry - A European Journal, 2009 , vol. 15, # 37 p. 9336 - 9349
反应条件
bis(acetylacetonato) palladium; N,N,N',N,-tetramethylethylenediamine; copper(I) bromide in 1-methyl-pyrrolidin-2-one T=170°C; 6 h; Inert atmosphere; chemoselective reaction;
参考文献
Cahiez, Gerard; Moyeux, Alban; Gager, Olivier; Poizat, Mael
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 4 p. 790 - 796
反应条件
2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl; N,N-dimethyl-aniline; silver carbonate; palladium dichloride T=150°C; 2 h;
参考文献
Wang, Zhiyong; Ding, Qiuping; He, Xiaodan; Wu, Jie
Tetrahedron, 2009 , vol. 65, # 24 p. 4635 - 4638
反应条件
sodium hydrogencarbonate; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide T=150°C; Suzuki-Miyaura cross-coupling reaction; 0.25 h; microwave irradiation;
参考文献
Appukkuttan, Prasad; Van Der Eycken, Erik; Dehaen, Wim
Synlett, 2005 , # 1 art. no. G33904ST, p. 127 - 133
反应条件
5 Pd/BaCO3 in isopropyl alcohol T=25°C; 12 h;
参考文献
Felpin, Francois-Xavier; Fouquet, Eric
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 6 p. 863 - 868
反应条件
1: ortho-nitrobenzoic acid With cupric(II) carbonate in various solvent(s) T=120°C; 0.5 h; 2: 1-bromo-4-methoxy-benzene With potassium fluoride; palladium acetylacetonate; iso-propyldiphenylphoshine in various solvent(s) T=120°C; 24 h; Further stages.;
参考文献
Goossen, Lukas J.; Rodriguez, Nuria; Melzer, Bettina; Linder, Christophe; Deng, Guojun; Levy, Laura M.
Journal of the American Chemical Society, 2007 , vol. 129, # 15 p. 4824 - 4833
反应条件
copper(l) iodide; PdI2; biphenyl-2-yl-di-tert-butyl-phosphane in 1-methyl-pyrrolidin-2-one T=160°C; 24 h; Inert atmosphere;
参考文献
Goossen, Lukas J.; Zimmermann, Bettina; Knauber, Thomas
Angewandte Chemie - International Edition, 2008 , vol. 47, # 37 p. 7103 - 7106
