2-氨基-5-苯基-1,3,4-噻二唑合成路线 （共 74 条）
反应条件
1.) acetone, heated water-bath, 1 h, 2.) reflux, 3 h; Yield given. Multistep reaction;
参考文献
Sridevi, G.; Rao, P. Jayaprasad; Reddy, K. Kondal
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 997 - 1000
反应条件
0.05 h; Microwave irradiation;
参考文献
Pattan; Kittur; Sastry; Jadav; Thakur; Madamwar; Shinde
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2011 , vol. 50, # 4 p. 615 - 618
反应条件
in water
0.05 h; Microwave irradiationSonicationGreen chemistry;
参考文献
Feng, Huangdi; Ying, Xili; Peng, Yanqing; Van Der Eycken, Erik V.; Liu, Chuanduo; Zhao, Shanshan; Song, Gonghua
Monatshefte fur Chemie, 2013 , vol. 144, # 5 p. 681 - 686
参考文献
Salimon, Jumat; Salih, Nadia; Ibraheem, Hanan; Yousif, Emad
Asian Journal of Chemistry, 2010 , vol. 22, # 7 p. 5289 - 5296
反应条件
in ethanol
5 h; Reflux;
参考文献
Raikwar; Srivastava
Journal of the Indian Chemical Society, 2008 , vol. 85, # 1 p. 78 - 84
反应条件
sulfuric acid in ethanol
Condensation; 4 h; Heating;
参考文献
Padhy, Arun Kumar; Nag; Panda
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1999 , vol. 38, # 8 p. 998 - 1001
反应条件
in ethanol
4 h; Heating;
参考文献
Yadav, L. D. S.; Shukla, K. N.; Singh, H.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1989 , vol. 28, # 1-11 p. 78 - 80
反应条件
1: acetone; dimethylformamide
2: NaOH / H2O / Heating
View Scheme
参考文献
Naik; Meher; Nayak
Journal of the Indian Chemical Society, 1983 , vol. 60, # 7 p. 674 - 678
反应条件
hydrogenchloride in ethanol
4 h; Heating;
参考文献
Khare, R. K.; Srivastava, M. K.; Singh, H.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1995 , vol. 34, # 9 p. 828 - 831
反应条件
1: 1) 48percent HBr, Br2, 2) NaNO2 / 2) water, 0 deg C, 30 min
2: 44 percent / EtONa / ethanol
3: 89 percent / K2CO3 / aq. ethanol / 8 h / Heating
4: 85 percent / K2CO3 / dimethylformamide / Ambient temperature
5: 78 percent / NaNO2, acetic acid / ethanol / 0.5 h
6: 1.2 g / Zn, formic acid / tetrahydrofuran; H2O / 1 h / 0 - 5 °C
7: 1M KOH / methanol / Ambient temperature
View Scheme
参考文献
Saito; Saheki; Hatanaka; Ishimaru
Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 1 p. 73 - 75
