反应条件
1: 97 percent / conc. H2SO4 / 15 h / Heating
2: 97 percent / conc. H2SO4, conc. HNO3 / 0.5 h / 0 °C
3: 91 percent / HCO2NH4 / Pd/C / methanol / 6 h / Heating
4: 99 percent / CuCl2, t-BuONO / acetonitrile / 0.5 h / 65 °C
5: 93 percent / LiBH4 / tetrahydrofuran / 1.) 0 deg C, 2 h, 2.) reflux, 4 h
6: 1.) DMSO, oxalyl chloride, 2.) Et3N / 1.) CH2Cl2, -78 deg C, 15 min, 2.) -78 deg C, 45 min, -78 deg C to room temperature, 10 min
View Scheme
参考文献
Burgess, Laurence E.
Synthetic Communications, 1997 , vol. 27, # 12 p. 2181 - 2191
