2-甲基-苯并噻唑-5-甲醛合成路线 （共 10 条）
反应条件
1: With tetrachloromethane; N-bromosuccinmide T=80°C; 4 h; UV-irradiation; 2: With 1,3,5,7-tetra-azatricyclo[5.1.1.13,5]decane; acetic acid in water T=110°C; 2 h;
参考文献
Tang, Li
Patent: EP2261221 A1, 2010 ;
Location in patent: Page/Page column 26 ;
反应条件
1: With 1,3,5,7-tetra-azatricyclo[5.1.1.13,5]decane; water; acetic acid T=110°C; 2 h; 2: With sodium hydrogencarbonate in ethyl acetate
参考文献
Tang, Li; Qiu, Rongguo
Patent: US2011/112149 A1, 2011 ;
Location in patent: Page/Page column 21-22 ;
反应条件
1.1: Na2S / 0.33 h / Heating 1.2: 77.6 percent / acetic acid / 0.33 h / Heating 2.1: lithium aluminum hydride / tetrahydrofuran / 2 h / Heating 3.1: 94.7 percent / SO3*pyridine; DMSO; triethylamine / CH2Cl2 / 2 h / 23 °C View Scheme
参考文献
Xu, Ju-Hua; Li, Yu-Liang; Zhu, Dao-Ben
Synthetic Communications, 2002 , vol. 32, # 11 p. 1647 - 1652
反应条件
1: lithium aluminum hydride / tetrahydrofuran / 2 h / Heating 2: 94.7 percent / SO3*pyridine; DMSO; triethylamine / CH2Cl2 / 2 h / 23 °C View Scheme
参考文献
Klar, Ulrich; Buchmann, Bernd; Schwede, Wolfgang; Skuballa, Werner; Hoffmann, Jens; Lichtner, Rosemarie B.
Angewandte Chemie - International Edition, 2006 , vol. 45, # 47 p. 7942 - 7948
反应条件
1: Na2S2 2: zinc / acetic acid 3: lithium aluminum hydride / diethyl ether / -40 °C 4: pyridinium chlorochromate View Scheme
参考文献
Xu, Ju-Hua; Li, Yu-Liang; Zhu, Dao-Ben
Synthetic Communications, 2002 , vol. 32, # 11 p. 1647 - 1652
反应条件
1: zinc / acetic acid 2: lithium aluminum hydride / diethyl ether / -40 °C 3: pyridinium chlorochromate View Scheme
参考文献
Xu, Ju-Hua; Li, Yu-Liang; Zhu, Dao-Ben
Synthetic Communications, 2002 , vol. 32, # 11 p. 1647 - 1652
反应条件
1: nitric acid; sulfuric acid 2: Na2S2 3: zinc / acetic acid 4: lithium aluminum hydride / diethyl ether / -40 °C 5: pyridinium chlorochromate View Scheme
参考文献
Xu, Ju-Hua; Li, Yu-Liang; Zhu, Dao-Ben
Synthetic Communications, 2002 , vol. 32, # 11 p. 1647 - 1652
反应条件
1: diethyl ether / 1.5 h / Heating 2: CrO3 / aq. acetic acid / 0.5 h / Heating View Scheme
参考文献
Zubarovskii,V.M.; Khodot,G.P.
J. Gen. Chem. USSR (Engl. Transl.), 1964 , vol. 34, p. 3801 - 3806,3852 - 3856
反应条件
1: With sodium hydroxide; silver nitrate in tetrahydrofuran; water T=20°C; 0.5 h; 2: With hydrogenchloride in water pH=3.5;
参考文献
TOYAMA CHEMICAL CO., LTD.; Hirono, Shuichi; Shiozawa, Shunichi
Patent: EP1445249 A1, 2004 ;
Location in patent: Page 132 ;
反应条件
zinc(II) chloride; lithium diisopropyl amide in tetrahydrofuran; hexane T=-70°C; Evans aldol addition; 1.5 h;
参考文献
Klar, Ulrich; Buchmann, Bernd; Schwede, Wolfgang; Skuballa, Werner; Hoffmann, Jens; Lichtner, Rosemarie B.
Angewandte Chemie - International Edition, 2006 , vol. 45, # 47 p. 7942 - 7948
