2-(苯基甲基)-1,3-苯并恶唑合成路线 （共 32 条）
反应条件
(Ru2(η5-C5Ph4O)2(H)2(CO)4); 2,6-dimethoxy-p-benzoquinone; bis(salicylideniminato-3-propyl)methylamino-cobalt(II) in chlorobenzene
T=120°C; 24 h;
参考文献
Endo, Yoshinori; Baeckvall, Jan-E.
Chemistry - A European Journal, 2012 , vol. 18, # 43 p. 13609 - 13613
反应条件
1: 55 percent / EDC; HOBt; DIPEA / CH2Cl2 / 24 h / 20 °C
2: 89 percent / CuI; Cs2CO3; 1,10-phenanthroline / 1,2-dimethoxy-ethane / 24 h / Heating
View Scheme
参考文献
Evindar, Ghotas; Batey, Robert A.
Journal of Organic Chemistry, 2006 , vol. 71, # 5 p. 1802 - 1808
反应条件
hydridotetrakis(triphenylphosphine)rhodium (Ph3P)4RhH; bis(1,2-diphenylphosphino)benzene in chlorobenzene
6 h; Inert atmosphereReflux;
参考文献
Li, Guangzhe; Arisawa, Mieko; Yamaguchi, Masahiko
Chemical Communications, 2014 , vol. 50, # 33 p. 4328 - 4330
反应条件
1: 55 percent / EDC; HOBt; DIPEA / CH2Cl2 / 24 h / 20 °C
2: 89 percent / CuI; Cs2CO3; 1,10-phenanthroline / 1,2-dimethoxy-ethane / 24 h / Heating
View Scheme
参考文献
Evindar, Ghotas; Batey, Robert A.
Journal of Organic Chemistry, 2006 , vol. 71, # 5 p. 1802 - 1808
反应条件
1: 1.20 g / (COCl)2 / CH2Cl2; dimethylformamide / 24 h / 20 °C
2: 89 percent / CuI; Cs2CO3; 1,10-phenanthroline / 1,2-dimethoxy-ethane / 24 h / Heating
View Scheme
参考文献
Evindar, Ghotas; Batey, Robert A.
Journal of Organic Chemistry, 2006 , vol. 71, # 5 p. 1802 - 1808
反应条件
hydridotetrakis(triphenylphosphine)rhodium (Ph3P)4RhH; bis(1,2-diphenylphosphino)benzene in chlorobenzene
6 h; Inert atmosphereReflux;
参考文献
Li, Guangzhe; Arisawa, Mieko; Yamaguchi, Masahiko
Chemical Communications, 2014 , vol. 50, # 33 p. 4328 - 4330
反应条件
hydridotetrakis(triphenylphosphine)rhodium (Ph3P)4RhH; bis(1,2-diphenylphosphino)benzene in chlorobenzene
6 h; Inert atmosphereReflux;
参考文献
Li, Guangzhe; Arisawa, Mieko; Yamaguchi, Masahiko
Chemical Communications, 2014 , vol. 50, # 33 p. 4328 - 4330
反应条件
1: methanol / Reflux
2: copper(l) iodide; lithium tert-butylate / 1,4-dioxane / 1.5 h / 120 °C / Inert atmosphere
View Scheme
参考文献
Zhao, Xia; Wu, Guojiao; Zhang, Yan; Wang, Jianbo
Journal of the American Chemical Society, 2011 , vol. 133, # 10 p. 3296 - 3299
反应条件
in chloroform
Ambient temperature;
参考文献
Braz,G.I. et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1967 , vol. 3, p. 158 - 162
Khimiya Geterotsiklicheskikh Soedinenii, 1967 , vol. 3, p. 215 - 219
反应条件
potassium hydroxide; tri-cyclo-hexyl-phosphine; di(acetonitrile)dichloropalladium in toluene; xylene
19 h; Heating;
参考文献
Niwa, Takashi; Yorimitsu, Hideki; Oshima, Koichiro
Organic Letters, 2007 , vol. 9, # 12 p. 2373 - 2375
