4-氯-5-甲基嘧啶-2-胺合成路线 （共 2 条）
反应条件
1: With trichlorophosphate 0.75 h; Reflux; 2: With ammonia in water T=10°C;
参考文献
Ruah, Sara Hadida; Miller, Mark; Zhou, Jinglan; Bear, Brian
Patent: US2009/221597 A1, 2009 ;
Location in patent: Page/Page column 41 ;
US 20090221597 A1
反应条件
ammonia; N-ethyl-N,N-diisopropylamine in 1,4-dioxane; water T=100°C; 0.25 h; IrradiationCEM discover microwave at 100W;
参考文献
WO2004/74278 A1, ;
Page 31-33 ;
WO 2004/074278 A1
