1-苄氧基-4-(2,2,2-三氟乙氧基)苯合成路线 （共 4 条）
反应条件
caesium carbonate in acetonitrile T=85°C; 3 h; Inert atmosphere;
参考文献
Yang, Qingliang; Njardarson, Jon T.
Tetrahedron Letters, 2013 , vol. 54, # 51 p. 7080 - 7082
反应条件
hydrogen; palladium on activated charcoal
参考文献
Koyama, Hiroo; Boueres, Julia K.; Miller, Daniel J.; Berger, Joel P.; MacNaul, Karen L.; Wang, Pei-Ran; Ippolito, Marc C.; Wright, Samuel D.; Agrawal, Arun K.; Moller, David E.; Sahoo, Soumya P.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 14 p. 3347 - 3351
反应条件
1: With lithium diisopropyl amide in tetrahydrofuran; hexane T=-78°C; 2 h; Inert atmosphere; 2: With MoO5*pyridine*HMPA in tetrahydrofuran; hexane T=-78°C; 2 h; Inert atmosphere; 3: With sodium hydrogencarbonate in tetrahydrofuran; methanol; hexane Inert atmosphere;
参考文献
Yang, Qingliang; Njardarson, Jon T.
Tetrahedron Letters, 2013 , vol. 54, # 51 p. 7080 - 7082
反应条件
1: 95 percent / H2 / Pd/C
2: SO2Cl2; diisobutylamine
View Scheme
参考文献
Koyama, Hiroo; Boueres, Julia K.; Miller, Daniel J.; Berger, Joel P.; MacNaul, Karen L.; Wang, Pei-Ran; Ippolito, Marc C.; Wright, Samuel D.; Agrawal, Arun K.; Moller, David E.; Sahoo, Soumya P.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 14 p. 3347 - 3351
