2-氨基-4-苯基噻唑合成路线 （共 144 条）
反应条件
1: Heating
2: NH3, PbO / ethanol
View Scheme
参考文献
Malik; Srivastava; Mehra
Journal of medicinal chemistry, 1968 , vol. 11, # 6 p. 1268 - 1269
反应条件
L-proline in methanol
T=20°C; 5 h;
参考文献
Kottawar; Goswami; Thorat; Bhusare
E-Journal of Chemistry, 2011 , vol. 8, # 4 p. 1859 - 1863
反应条件
piperidine in ethanol
T=70 - 80°C; 0.75 h;
参考文献
Dash, B.; Patra, M.; Praharaj, S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 10 p. 894 - 897
反应条件
1: 83 percent / pyridine / Ambient temperature
2: PCl5 / 1.5 h / 130 °C
3: sodium azide, sodium acetate / acetone; H2O / 8 h
4: 50 percent / decahydronaphthalene / 2 h / Heating
View Scheme
参考文献
Ramachandraiah, G.; Reddy, K. Kondal
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1985 , vol. 24, p. 808 - 810
反应条件
triethylamine in ethanol
3 h; Heating;
参考文献
Abdelhamid, Abdou O.; Hassaneen, Hamdi M.; Shawali, Ahmad S.; Parkanyi, Cyril
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 639 - 644
参考文献
Madan; Taneja; Kudesia
Journal of the Indian Chemical Society, 1991 , vol. 68, # 8 p. 471 - 472
反应条件
1: 1.) acetone, reflux, 1 h, 2.) acetone, reflux
2: 88 percent / NaOH (10 percent) / H2O / Heating
3: 66 percent / ethanol / 1.5 h / Heating
View Scheme
参考文献
Sawhney, S. N.; Dhindsa, G. S.; Singh, S. P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 10 p. 1044 - 1049
反应条件
2: NH2NH2•xH2O / ethanol
View Scheme
参考文献
Pattan; Ali, M. Shamrez; Purohit; Reddy; Nataraj
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 8 p. 1929 - 1932
反应条件
in acetone
2 h; Heating;
参考文献
ABBOTT GMBH and CO. KG
Patent: WO2005/82871 A2, 2005 ;
Location in patent: Page/Page column 74 ;
WO 2005/082871 A2
反应条件
in acetone
1 h; Heating; Yield given;
参考文献
Dhindsa, G. S.
Polish Journal of Chemistry, 1986 , vol. 60, # 4-6 p. 609 - 614
