丁氧羰基- PHG-OSU合成路线 （共 3 条）
反应条件
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in N,N-dimethyl-formamide
18 h; Ambient temperature;
参考文献
DeSolms; Giuliani; Guare; Vacca; Sanders; Graham; Wiggins; Darke; Sigal; Zugay; Emini; Schleif; Quintero; Anderson; Huff
Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2852 - 2857
反应条件
1: aq. NaHCO3 / tetrahydrofuran / 12 h / 23 °C
2: 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide / dioxane / 2 h / 23 °C
View Scheme
参考文献
Nicolaou; Hughes, Robert; Pfefferkorn, Jeffrey A.; Barluenga, Sofia; Roecker
Chemistry - A European Journal, 2001 , vol. 7, # 19 p. 4280 - 4295
反应条件
1: aq. NaHCO3 / tetrahydrofuran / 12 h / 23 °C
2: 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide / dioxane / 2 h / 23 °C
View Scheme
参考文献
Nicolaou; Hughes, Robert; Pfefferkorn, Jeffrey A.; Barluenga, Sofia; Roecker
Chemistry - A European Journal, 2001 , vol. 7, # 19 p. 4280 - 4295
