二甲基氨基甲亚基-二甲基铵硫酸甲酯盐合成路线 （共 12 条）
反应条件
in tetrahydrofuran T=60°C; 1 h;
参考文献
NOVARTIS AG
Patent: WO2009/90251 A2, 2009 ;
Location in patent: Page/Page column 143-144 ;
参考文献
Bredereck,H. et al.
Chemische Berichte, 1971 , vol. 104, p. 924 - 931
反应条件
in tetrahydrofuran T=60°C; 1 h;
参考文献
NOVARTIS AG
Patent: WO2009/90251 A2, 2009 ;
Location in patent: Page/Page column 143-144 ;
反应条件
1: dimethyl amine With boric acid trimethyl ester; sodium hydride in tetrahydrofuran deprotonation; complexation; cooling; 2: N,N,N',N'-tetramethylformamidinium methyl sulfate in tetrahydrofuran Addition; cooling;
参考文献
Kantlehner, Willi; Stieglitz, Ruediger; Hauber, Michael; Haug, Erwin; Regele, Claudia
Journal fuer Praktische Chemie - Practical Applications and Applied Chemistry (Germany), 2000 , vol. 342, # 3 p. 256 - 268
反应条件
ethyl mercaptan sodium salt in diethyl ether Heating;
参考文献
Bredereck,H. et al.
Chemische Berichte, 1973 , vol. 106, p. 3725 - 3731
反应条件
sodium nitrite in water T=99.9°C; 5 h; Yield given. Yields of byproduct given;
参考文献
Gouesnard, Jean-Paul; Dorie, Jean
Bulletin de la Societe Chimique de France, 1985 , # 1 p. 132 - 136
反应条件
sodium nitrite in water T=99.9°C; 5 h; Yield given. Yields of byproduct given;
参考文献
Gouesnard, Jean-Paul; Dorie, Jean
Bulletin de la Societe Chimique de France, 1985 , # 1 p. 132 - 136
反应条件
in tetrahydrofuran T=60°C; 1 h;
参考文献
NOVARTIS AG
Patent: WO2009/90251 A2, 2009 ;
Location in patent: Page/Page column 143-144 ;
反应条件
in diethyl ether 1 h;
参考文献
Wasserman, Harry H.; Ives, Jeffrey L.
Journal of Organic Chemistry, 1985 , vol. 50, # 19 p. 3573 - 3580
反应条件
in diethyl ether Heating;
参考文献
Wasserman, Harry H.; Ives, Jeffrey L.
Journal of Organic Chemistry, 1985 , vol. 50, # 19 p. 3573 - 3580
