1: With E. coli T=30°C; Baeyer-Villiger oxidation; 36 h; Enzymatic reaction; 2: With hydrogen; toluene-4-sulfonic acid; palladium on activated charcoal in methanol; water 5 h; Title compound not separated from byproducts;

<b>Multi-step reaction with 3 steps<br /> </b>1: 87 percent / LiAlH₄ / tetrahydrofuran / 15 h / 0 &deg;C<br />2: NaH / tetrahydrofuran<br />3: 90 percent / HCl / acetone / 2 h / 20 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 95 percent / LAH / tetrahydrofuran<br />2: 98 percent / NaH / tetrahydrofuran / 0 &deg;C<br />3: 92 percent / aq. H₂SO₄ / tetrahydrofuran<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 90 percent / p-TSA / benzene<br />2: 95 percent / LAH / tetrahydrofuran<br />3: 98 percent / NaH / tetrahydrofuran / 0 &deg;C<br />4: 92 percent / aq. H₂SO₄ / tetrahydrofuran<br /> <br /> &nbsp;