(2,6-二甲基苯氧基)乙酰氯合成路线 （共 4 条）
反应条件
sodium hydrogencarbonate in water; ethyl acetate T=20 - 25°C; 1.16667 h;
参考文献
Ambati, V Raghava Reddy; Garaga, Srinivas; Dandala, Ramesh; Meenakshisunderam, Sivakumaran
Patent: US2010/317855 A1, 2010 ;
Location in patent: Page/Page column 5 ;
参考文献
Abbott Laboratories
Patent: EP1170289 A2, 2002 ;
Location in patent: Page 25 ;
反应条件
1: (2S,3S,5S)-2-amino-3-hydroxy-5-tert-butoxycarbonylamino-1,6-diphenylhexane succinate With sodium hydrogencarbonate in water; ethyl acetate T=20°C; 0.666667 h; 2: 2,6-dimethylphenoxyacetyl chloride in water; ethyl acetate T=15 - 20°C; 1.75 h;
参考文献
RANBAXY LABORATORIES LIMITED
Patent: WO2006/90264 A1, 2006 ;
Location in patent: Page/Page column 20-21 ;
反应条件
1: (2S,3S,5S)-2-amino-3-hydroxy-5-(t-butyloxycarbonylamino)-1,6-diphenylhexane succinate With sodium hydrogencarbonate in water; ethyl acetate 0.25 h; 2: 2,6-dimethylphenoxyacetyl chloride in ethyl acetate 0.5 h;
参考文献
Abbott Laboratories
Patent: EP1170289 A2, 2002 ;
Location in patent: Page 55 ;
