H3[PW12O40] in water T=20°C; 0.1 h; regioselective reaction;

potassium carbonate; copper acetylacetonate in toluene T=50°C; Arylation; 6 h;

toluene-4-sulfonic acid in ethanol T=80°C; 24 h; Inert atmosphere;

1: 4-methyl-chlorobenzene With BrettPhos Palladacycle; sodium t-butanolate; hydrazine in tetrahydrofuran T=20°C; 0.1 h; Flow reactorSonicationInert atmosphere; 2: acetylacetone With trifluoroacetic acid in THF-d8 (tetrahydrofuran-d8); water T=60°C; 0.1 h; Flow reactorSonicationInert atmosphere;

Cu-exchanged fluoroapatite; air in methanol T=20°C; 24 h;