N-苄氧羰基-L-亮氨酸合成路线 (共 125 条)
反应条件
sulfuric acid in water; ethyl acetate Cooling with ice;
参考文献
Loeser, Reik; Frizler, Maxim; Schilling, Klaus; Guetschow, Michael
Angewandte Chemie - International Edition, 2008 , vol. 47, # 23 p. 4331 - 4334
反应条件
triethylamine in 1,4-dioxane; water
参考文献
Saino; Someno; Miyazaki; Ishii
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 7 p. 2319 - 2325
反应条件
phosphate buffer; α-chymotrypsin in dimethyl sulfoxide T=-24°C; pH=8.0; 24 h;
参考文献
Tetrahedron Asymmetry, , vol. 17, # 1 p. 22 - 29
反应条件
antibody 7G12; Tris buffer; water in dimethyl sulfoxide T=25°C; Rate constant;
参考文献
Journal of the American Chemical Society, , vol. 118, # 10 p. 2332 - 2339
反应条件
sodium trimethyl-silanolate in tetrahydrofuran T=20°C; 4.5 h;
参考文献
Croatica Chemica Acta, , vol. 80, # 1 p. 109 - 115
反应条件
1: 74 percent / tetrahydrofuran / 6 h / 30 °C 2: 74 percent / DBU, morpholine / Pd(dba)2, PPh3 / acetonitrile / 12 h / 30 °C View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 11 p. 1623 - 1627
反应条件
1: 74 percent / tetrahydrofuran / 6 h / 30 °C 2: 74 percent / DBU, morpholine / Pd(dba)2, PPh3 / acetonitrile / 12 h / 30 °C View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 11 p. 1623 - 1627
反应条件
1: Et3N, 1,1-carbonyldiimidazole / dimethylformamide / 2 h / Ambient temperature 2: NaOH / methanol / 3 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 39, # 20 p. 4089 - 4098
反应条件
jones' reagent in acetone T=0°C; 3 h; Yield given. Yields of byproduct given;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 535 - 540
反应条件
sodium hydrogencarbonate; sodium carbonate in water; acetonitrile T=50°C; Substitution; pH=9.5; 1 h;
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 43, # 5 p. 449 - 461