N-苄氧羰基-L-亮氨酸合成路线 （共 125 条）
反应条件
1: (i) ClCO2Et, Et3N, CHCl3, (ii) /BRN= 1722028/ 2: aq. NaOH / acetone 3: H2, AcOH / Pd / methanol; H2O View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 46, p. 2190 - 2193
反应条件
papain in water; N,N-dimethyl-formamide T=38°C; 24 h; ethylenediaminetetraacetic acid, cysteine hydrochloride, pH 4.8;
参考文献
Cerovsky, Vaclav; Jost, Karel
Collection of Czechoslovak Chemical Communications, 1984 , vol. 49, # 11 p. 2557 - 2561
反应条件
benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine in dichloromethane T=0 - 20°C;
参考文献
Voelkert, Martin; Koul, Surrinder; Mueller, Gernot H.; Lehnig, Manfred; Waldmann, Herbert
Journal of Organic Chemistry, 2002 , vol. 67, # 20 p. 6902 - 6910
反应条件
1: Et3N / tetrahydrofuran / 0.17 h / -10 °C 2: methanol / 1 h / 20 °C View Scheme
参考文献
Verardo, Giancarlo; Geatti, Paola; Lesa, Barbara
Synthesis, 2005 , # 4 art. no. P11004SS, p. 559 - 564
反应条件
3,3'-Dicyano-4,4',6,6'-tetramethyl-2,2'-dipyridinyl-disulfid; triphenylphosphine in dichloromethane T=-20 - -15°C; 12 h;
参考文献
Schmidt, Ulrich; Potzolli, Bernd
Liebigs Annalen der Chemie, 1987 , p. 935 - 942
反应条件
Sephadex G-50; triethylamine; bromelain in ethyl acetate T=37°C; 7 h;
参考文献
Tai, Dar-Fu; Fu, Shu-Lin
Journal of the Chinese Chemical Society, 2003 , vol. 50, # 1 p. 179 - 183
反应条件
tetraethyl pyrophosphite
参考文献
Vaughan; Osato
Journal of the American Chemical Society, 1952 , vol. 74, p. 676
反应条件
sodium dioctyl sulfosuccinate in 2,2,4-trimethylpentane; water 48 h; Product distribution;
参考文献
Ranganathan, D.; Singh, G. P.; Ranganathan, S.
Journal of the American Chemical Society, 1989 , vol. 111, # 3 p. 1144 - 1145
反应条件
sodium dioctyl sulfosuccinate in 2,2,4-trimethylpentane; water 48 h; Product distribution;
参考文献
Ranganathan, D.; Singh, G. P.; Ranganathan, S.
Journal of the American Chemical Society, 1989 , vol. 111, # 3 p. 1144 - 1145
反应条件
1: 1.) N-ethylmorpholine, isobutyl chloroformate / 1.) THF, -15 deg C, 5 min; 2.) THF/EtOH, -15 deg C to rt., 20 min 2: H2 / 5percent Pd/C / aq. acetic acid / Ambient temperature 3: pyridine / 0.25 h / -15 °C View Scheme
参考文献
Blackburn, G. Michael; Lilley, Terence H.; Milburn, Peter J.
Journal of the Chemical Society, Faraday Transactions 1: Physical Chemistry in Condensed Phases, 1985 , vol. 81, p. 2191 - 2206
