[(3S,4R)-1-苄基-4-(4-氟苯基)-3-哌啶基]甲醇合成路线 （共 22 条）
反应条件
1: dioxane / 2 h / 115 °C
2: 76 percent / Bu4NF
View Scheme
参考文献
Igarashi, Junji; Ishiwata, Hiroyuki; Kobayashi, Yuichi
Tetrahedron Letters, 2004 , vol. 45, # 43 p. 8065 - 8068
反应条件
1.1: chiral bis-lithium amide base / tetrahydrofuran; hexane / 0.75 h / -78 °C
1.2: 71 percent / tetrahydrofuran; hexane / -40 °C
2.1: LiAlH4 / tetrahydrofuran / Heating
View Scheme
参考文献
Gill, Christopher D.; Greenhalgh, Daniel A.; Simpkins, Nigel S.
Tetrahedron, 2003 , vol. 59, # 46 p. 9213 - 9230
