(3R,4S)-3-(1-乙氧乙氧基)-2-氧-4-苯基-吖丁啶羧酸叔丁基酯合成路线 (共 4 条)
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in dichloromethane
参考文献
Ojima, Iwao; Sun, Chung Ming; Zucco, Martine; Park, Young Boon; Duclos, Olivier; Kuduk, Scott
Tetrahedron Letters, 1993 , vol. 34, # 26 p. 4149 - 4152
反应条件
1: 100 percent / H(1+) 2: 93 percent / Et3N, DMAP / CH2Cl2 View Scheme
参考文献
Tetrahedron Letters, , vol. 34, # 26 p. 4149 - 4152
反应条件
1: 100 percent / NBu4F / tetrahydrofuran 2: 100 percent / H(1+) 3: 93 percent / Et3N, DMAP / CH2Cl2 View Scheme
参考文献
Tetrahedron Letters, , vol. 34, # 26 p. 4149 - 4152
反应条件
1: sodium hexamethyldisilazane; sodium hydride / tetrahydrofuran / 2.5 h / -40 °C 2: palladium on carbon; hydrogen / tetrahydrofuran / 5 h / 20 °C 3: acetic acid / water / 4 h / 20 °C View Scheme
参考文献
Zhou, Hui; Chen, Dahai; Gao, Hongwei; Li, Qingeng
Letters in Organic Chemistry, 2010 , vol. 7, # 6 p. 450 - 452