N,N-二乙基-2-羟基-2-苯乙酰胺合成路线 （共 11 条）
反应条件
hydrogen; Ru clay in benzene
T=75°C; P=25857.4 Torr; 60 h;
参考文献
Aldea, Raluca; Alper, Howard
Journal of Organic Chemistry, 1998 , vol. 63, # 25 p. 9425 - 9426
反应条件
lithium diisopropyl amide in tetrahydrofuran
T=-78°C; 6 h;
参考文献
Zhang, Pingsheng; Gawley, Robert E.
Journal of Organic Chemistry, 1993 , vol. 58, # 12 p. 3223 - 3224
反应条件
in acetonitrile
T=45°C; P=6000480 Torr; 96 h;
参考文献
Matsumoto, Kiyoshi; Hashimoto, Shiro; Uchida, Takane; Okamoto, Tadashi; Otani, Shinichi
Chemische Berichte, 1989 , vol. 122, p. 1357 - 1364
反应条件
1: 1.) KH / 1.) THF, r.t., 20 min, 2.) 2 h
2: 86 percent / LDA / tetrahydrofuran / 6 h / -78 °C
View Scheme
参考文献
Zhang, Pingsheng; Gawley, Robert E.
Journal of Organic Chemistry, 1993 , vol. 58, # 12 p. 3223 - 3224
反应条件
1: 1.) KH / 1.) THF, r.t., 20 min, 2.) 2 h
2: 86 percent / LDA / tetrahydrofuran / 6 h / -78 °C
View Scheme
参考文献
Zhang, Pingsheng; Gawley, Robert E.
Journal of Organic Chemistry, 1993 , vol. 58, # 12 p. 3223 - 3224
反应条件
triethylamine in acetonitrile
Irradiation;
参考文献
Cossy, Janine; Madaci, Abdelaziz; Pete, Jean-Pierre
Tetrahedron Letters, 1994 , vol. 35, # 10 p. 1541 - 1544
反应条件
1: 1.) DMAP, pyridine, 2.) oxalyl chloride, DMF / 1.) CH2Cl2, RT, 4 h, 2.) CH2Cl2, a.) 0 deg C, 1 h, b.) RT, 30 min
2: pyridine / CH2Cl2 / 2 h / Ambient temperature
3: citric acid / methanol / 0.5 h
View Scheme
参考文献
Kelly; LaCour
Synthetic Communications, 1992 , vol. 22, # 6 p. 859 - 869
反应条件
1: pyridine / CH2Cl2 / 2 h / Ambient temperature
2: citric acid / methanol / 0.5 h
View Scheme
参考文献
Kelly; LaCour
Synthetic Communications, 1992 , vol. 22, # 6 p. 859 - 869
反应条件
tBuOOLi; lithium diisopropyl amide
1.) hexane, THF, 0 deg C; 2.) toluene, 2 h, 25 deg C; Yield given. Multistep reaction;
参考文献
Julia, Marc
Bulletin de la Societe Chimique de France, 1996 , vol. 133, # 1 p. 15 - 24
反应条件
oxygen in N,N-dimethyl-formamide
electrolysis; Product distribution;
参考文献
Sugawara, M.; Baizer, M. M.; Monte, W. T.; Little, R. D.; Hess, U.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1983 , vol. 37, # 6 p. 509 - 518
