1,3,3-三甲基-2,3-二氢-1H-吲哚-2-酮合成路线 （共 67 条）
参考文献
Brunner
Monatshefte fuer Chemie, 1897 , vol. 18, p. 115,116
Monatshefte fuer Chemie, 1895 , vol. 16, p. 864
参考文献
Brunner
Monatshefte fuer Chemie, 1897 , vol. 18, p. 533
参考文献
Brunner
Monatshefte fuer Chemie, 1896 , vol. 17, p. 272
Monatshefte fuer Chemie, 1897 , vol. 18, p. 109 Anm.1
参考文献
Kuhn et al.
Chemische Berichte, 1930 , vol. 63, p. 3176,3182
参考文献
Kuhn et al.
Chemische Berichte, 1930 , vol. 63, p. 3176,3182
反应条件
1: 69 percent / NCS / 2-methyl-propan-2-ol / 17 h / 50 °C
2: 87 percent / LiAlH4 / diethyl ether / R.T, 2 h then reflux, 2 h
View Scheme
参考文献
Fukui; Endo; Oishi
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 12 p. 3639 - 3648
反应条件
1: 60 percent / 65 percent HNO3 / acetic acid / 24 h / Ambient temperature
2: 57.8 g / hydrogen / 10 percent Pd/C / methanol / 760 Torr / Ambient temperature
View Scheme
参考文献
Saal, Wolfgang von der; Hoelck, Jens-Peter; Kampe, Wolfgang; Mertens, Alfred; Mueller-Beckmann, Bernd
Journal of Medicinal Chemistry, 1989 , vol. 32, # 7 p. 1481 - 1491
