1,2-bis(di-tert-butylphosphino)benzene; methanesulfonic acid; palladium diacetate in toluene P=4560 Torr; 12 h; Heating; Title compound not separated from byproducts;
1: chloroformic acid ethyl ester; phenylpropionic acid sodium salt in tetrahydrofuran T=20°C; 0.25 h; 2: n-Bu-ZnI With tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran T=70°C; Negishi-type cross-coupling; 14 h; Title compound not separated from byproducts;
1: N-methyl-3-phenylpropionamide With pyridine; trifluoromethanesulfonic acid anhydride in dichloromethane T=-40 - 20°C; 2: ethanol in dichloromethane T=20°C; 0.166667 h; 3: With (NH4)2S in dichloromethane; water T=-15°C; 2 h;
参考文献
Journal of Organic Chemistry, , vol. 68, # 14 p. 5792 - 5794
