4,5-二氢-2-(6-羟基-2-苯并噻唑)-4-噻唑羧酸合成路线 (共 13 条)
反应条件
1: (i) P2S5, xylene, (ii) K3<Fe(CN)6>, aq. NaOH 2: HCl 3: NH3 / methanol 4: POCl3 5: Py*HCl / 200 °C View Scheme
参考文献
White,E.H. et al.
Journal of the American Chemical Society, 1963 , vol. 85, p. 337 - 343
反应条件
1: HCl 2: NH3 / methanol 3: POCl3 4: Py*HCl / 200 °C View Scheme
参考文献
White,E.H. et al.
Journal of the American Chemical Society, 1963 , vol. 85, p. 337 - 343
反应条件
potassium phenolate in dimethyl sulfoxide under high vacuum;
参考文献
White, Emil H.; Steinmetz, Mark G.; Miano, Jeffrey D.; Wildes, Peter D.; Morland, Robert
Journal of the American Chemical Society, 1980 , vol. 102, # 9 p. 3199 - 3208
反应条件
1: dimethylsulfoxide / 2.5 h / 125 °C 2: Py*HCl / 2 h / 185 - 195 °C View Scheme
参考文献
White,E.H. et al.
Journal of the American Chemical Society, 1963 , vol. 85, p. 337 - 343
反应条件
1: NH3 / methanol 2: POCl3 3: Py*HCl / 200 °C View Scheme
参考文献
White,E.H. et al.
Journal of the American Chemical Society, 1963 , vol. 85, p. 337 - 343
反应条件
sodium hydroxide in water T=110°C;
参考文献
Suzuki,N. et al.
Tetrahedron, 1972 , vol. 28, p. 4065 - 4074
反应条件
1: Py*HCl / 2 h / 185 - 195 °C View Scheme
参考文献
White,E.H. et al.
Journal of the American Chemical Society, 1963 , vol. 85, p. 337 - 343
反应条件
1: Py*HCl / 200 °C View Scheme
参考文献
White,E.H. et al.
Journal of the American Chemical Society, 1963 , vol. 85, p. 337 - 343
反应条件
1: POCl3 2: Py*HCl / 200 °C View Scheme
参考文献
White,E.H. et al.
Journal of the American Chemical Society, 1963 , vol. 85, p. 337 - 343
参考文献
White,E.H. et al.
Journal of the American Chemical Society, 1963 , vol. 85, p. 337 - 343
Full Text View citing articles Show Details
White,E.H. et al.
Journal of Organic Chemistry, 1965 , vol. 30, p. 2344 - 2348