2-甲氧基-3-氨基吡啶合成路线 （共 14 条）
反应条件
hydrogen; palladium on activated charcoal in tetrahydrofuran; methanol T=20°C; Hydrogenation; 1 h;
参考文献
Dolle, Valerie; Nguyen, Chi Hung; Bisagni, Emile
Tetrahedron, 1997 , vol. 53, # 37 p. 12505 - 12524
反应条件
sodium hydroxide anschliessendes Hydrieren an Palladium/CaCO3;
参考文献
Chemische Berichte, , vol. 68, p. 315,321
反应条件
sodium hydroxide; bromine in tetrahydrofuran T=5 - 70°C; Hoffmann rearrangement;
参考文献
Journal of Medicinal Chemistry, , vol. 50, # 24 p. 6265 - 6273
反应条件
sodium methylate; copper T=150°C;
参考文献
Chemische Berichte, , vol. 69, p. 2593,2604
反应条件
1: concentrated aqueous HCl 2: methanol. sodium methylate; copper-powder / 150 °C View Scheme
参考文献
Chemische Berichte, , vol. 69, p. 2593,2604
反应条件
N-bromosuccinmide in N,N-dimethyl-formamide T=-30°C;
参考文献
TAISHO PHARMACEUTICAL CO., LTD; NISSAN CHEMICAL INDUSTRIES, LTD.
Patent: US2011/237791 A1, 2011 ;
Location in patent: Page/Page column 64 ;
反应条件
N,N-dimethyl-formamide; trichlorophosphate T=130°C; 24 h;
参考文献
Lai, Long-Li; Lin, Pen-Yuan; Wang, Jy-Shih; Hwu, Jih Ru; Shiao, Min-Jen; Tsay, Shwu-Chen
Journal of Chemical Research - Part S, 1996 , # 4 p. 194 - 195
反应条件
1: With hydrogenchloride; sodium nitrite in water T=0°C; 0.5 h; 2: With hydrogenchloride; SnCl2·2H2O in water T=0°C; 1.5 h; 3: With potassium hydroxide in water
参考文献
Jeanty, Matthieu; Blu, Jerome; Suzenet, Franck; Guillaumet, Gerald
Organic Letters, 2009 , vol. 11, # 22 p. 5142 - 5145
反应条件
triethylamine in tetrahydrofuran; diethyl ether 20 h;
参考文献
Estel; Linard; Marsais; Godard; Queguiner
Journal of Heterocyclic Chemistry, 1989 , vol. 26, # 1 p. 105 - 112
反应条件
in 1,4-dioxane 24 h; Reflux;
参考文献
Badland, Matthew; Devillers, Ingrid; Durand, Corinne; Fasquelle, Veronique; Gaudillire, Bernard; Jacobelli, Henry; Manage, Ajith C.; Pevet, Isabelle; Puaud, Jocelyne; Shorter, Anthony J.; Wrigglesworth, Roger
Tetrahedron Letters, 2011 , vol. 52, # 41 p. 5292 - 5296
