n-butyllithium; N,N,N',N,-tetramethylethylenediamine in tetrahydrofuran T=-100°C; 0.00833333 h;

potassium carbonate in dimethyl sulfoxide 1.5 h; Ambient temperature;

1: tert.-butylnitrite; trimethylsilylazide / acetonitrile / 4.67 h / 60 °C / Automated synthesizer 2: acetonitrile / 4.5 h / 60 °C / 5171.62 Torr / Automated synthesizer View Scheme

hydrogenchloride; trichlorophosphate 1.) DMF, 0 deg C, 5 min, 25 deg C, 10 min, 80 deg C, 15 min, 2.) DMF, water, 80 deg C, 5 min; Multistep reaction;